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By V. Zakosh. Thomas Aquinas College, Santa Paula CA. 2018.

Bone loss in menopausal women and a higher rate of vertebral or spinal fractures are also associated with higher 32 cortisol levels discount 200mg red viagra free shipping erectile dysfunction testosterone injections. When we breathe shallowly all day purchase red viagra 200mg without prescription best erectile dysfunction pills review, similar to a rabbit, emergency “sensors” alert the body that we’re under attack and need a constant flow of adrenaline and cortisol. Instead, when you breathe into the lower lobes of the lungs, calming sensors tell your body to settle down. Breathing through the nose, slowly and deeply, is especially effective in triggering the calm response. Getting into the present moment is your ticket to normalizing cortisol (assuming you’re not exchanging gunfire at this moment and require sharp focus). Most women I know unconsciously grip their muscles, whether in the jaw, neck, shoulders, or lower back. Any time you put your feet above the level of your heart, even with your legs straight up against the wall, you activate your parasympathetic nervous system, the rest-and-digest counterbalance to fight or flight (or tend and befriend in women) of the sympathetic nervous system. The final pose of a yoga practice, called Savasana in Sanskrit, which means “corpse pose,” is considered the most important, and most difficult, pose because it is where you integrate the key stress-relieving practices. While lying flat on your back, close your eyes, breathe deeply, and tune in to a clear state of mind and subtle shifts of energy in your body. Part B: The Nitty- Gritty on Low Cortisol It may sound counterintuitive, but after you’ve had continuous high cortisol, low cortisol often follows. Irritability, burnout, and depression are common symptoms, along with low blood pressure, orthostatic hypotension (which is when your blood pressure drops when you stand and you feel light-headed), and uncharacteristic pessimism. It wasn’t long ago that I was addicted to all the things that I preach against—sugar, adrenaline, and caffeine. At Harvard Medical School, I was taught (and blithely internalized) the message that the ruthless and dogged pursuit of medical knowledge was noble, even if it meant denying basic needs. It took me years to recognize my problem with cortisol, mostly because I never learned about it in medical school, and neither had the mainstream doctors whom I saw due to my symptoms. I discovered that the only doctors who are aware of adrenal dysregulation are the ones who developed the problem themselves. Otherwise, I find that mainstream health providers don’t believe in the existence of adrenal burnout. I want you to care about this because it may be happening to you right now, as you multitask and read this book. I want you to prevent the potential crash of your health because of persistent stress, and if you’re already experiencing the symptoms of adrenal anarchy, the good news is that I came back to normal and you can too. Mind the Gap: You’re Not Crazy Even If Your Doctor Ignores Your Symptoms Low cortisol is an issue that you won’t hear about from a mainstream medical doctor unless you are flat on your back, in adrenal crisis, with blood pressure so low that you can’t send oxygen to your brain. I love mainstream, or allopathic, medicine—I’m board certified in it, and many of my closest friends are mainstream physicians. Low-grade symptoms such as fatigue, anxiety, and stress plague most of my clients, yet they were not well addressed in my own allopathic medical training, so it’s not surprising that women with these issues have trouble finding solutions in mainstream medicine. Hypocortisolism, Explained Hypocortisolism, or low cortisol, occurs when your adrenal glands are unable to make a normal amount of the main stress hormone, cortisol. Second only to hypercortisolism, or high cortisol, hypocortisolism is the next most common hormonal imbalance I find in my patients. Eventually, it waves the white flag of surrender, exhausted; that’s when you have low cortisol. In addition to cortisol, the adrenals release other hormones and neurotransmitters, including the following: • Pregnenolone is made from cholesterol and serves to reduce your anxiety. It’s considered the “mother” hormone because all other sex steroids—such as estrogens, progesterone, cortisol, testosterone, and aldosterone—are made from it. The Science of Low Cortisol Warning: If you are an overachiever and want more information, this section is for you, but please know this is a trait that puts you at greater risk for adrenal dysregulation. If all this talk is actually wigging you out a bit, feel free to skip this section, and go directly to “Part B: The Gottfried Protocol for Low Cortisol” (page 116). Causes of Low Cortisol The following conditions are causes of low cortisol, all of which are documented in mainstream medicine. This occurs when the adrenal glands fail to make enough cortisol, typically caused by the body’s own immune system attacking the adrenal glands and ultimately destroying them. Kennedy was the most famous person to have Addison’s, although his handlers concealed his diagnosis from the public.

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In particular cheap 200mg red viagra with mastercard erectile dysfunction protocol by jason, the antiestrogen drug tamoxifen prevents stimulation of cancer- ous breast tumor cells by estrogens cheap 200 mg red viagra mastercard erectile dysfunction drugs and alcohol. This also applies to aminoglutethimide, an inhibitor of corticosteroid synthesis by the adrenal glands. Hormone-sensitive tumors may regress, and frequently stop growth upon introduction of certain hormones. The main hormone-sensitive forms of cancer are breast and prostate car- cinoma, lymphoma, and a few other forms of carcinomas. Hormonal drugs that inhibit growth of certain human tumors are steroids, including andro- gens, estrogens, progestins, and corticosteroids, although only glucocorticoids are used. Moreover, neither cortisol nor cortisone are used to treat malignant tumors, but instead pred- nisone, prednisolone, methylprednisolone, and dexametasone are used. Hormonal drugs do not cure cancer, although they do exhibit pronounced palliative action, with the exception of the cytotoxic action of glucocorticoids on lymphoid cells. In particu- lar, this concerns predinsone, which is used to treat lymphomas and certain leukemias in combination therapy. However, it is presumed that androgens block cell growth by inhibiting transport of natural hormone into the cell. Moreover, androgens can inhibit estrogen synthesis, thus depleting estrogen reserves. It is highly probable that the mechanism of action is similar to the mechanism of action of androgens. Progestins can have a direct local effect on cells, and can simultaneously lower the quantity of leutenizing hormone. Corticosteroids exhibit an antitumor effect by binding with cor- ticosteroid receptors that exist in many cancerous lymphoma cells, which leads to inhibition of both glucose transport and phosphorylation, which reduces the amount of energy neces- sary for mitosis and protein synthesis, which, accordingly, leads to cell lysis. Reducing the nitro group with hydrogen over a nickel catalyst gives the desired aminoglutethimide (30. The last, in Michael addition reaction conditions, in the presence of benzyltrimethylammonia hydroxide is added to methylacrylate, and the obtained product undergoes acidic hydrolysis by a mixture of acetic and sulfuric acids, during which a cyclyzation to 2-(4-nitrophenyl)-2-ethylglutarim- ide (30. Aminoglutethimide is used for palliative treatment of prostate carcinomas and post-menopausal breast carcinomas. Tamoxifen is used for palliative treatment of breast cancer in pre- and post-menopausal women. Leuprolide is used for prostate cancer, when orchiectomy or estrogen therapy is counter- productive to the patient. In this reaction, hydroxylamine hydrochloride and a basic ion-exchange resin are used [140,141]. This drug causes a sharp increase in the amount of white blood cells in severe leukemias. It is synthesized from danthron (1,8-dihydroxyanthraquinone), which when reacted with nitric acid, and then a mixture of sodium sulfide and thiosulfate in a base, is transformed to 1,4,5,8-tetrahydroxyanthraquinone (30. Reacting this with 2-amino- ethylaminoethanol in the presence of chloranyl (2,3,5,6-tetrachlorobenzoquinone-1,4) gives the desired mitoxantrone (30. It is used intravenously for treating severe nonlymphatic leukemia, breast cancer, and so on. Dacarbazine is used intravenously for Hodgkin’s disease, soft-tissue sarcoma, and metastatic melanoma. The carbomethoxy group of this molecule is hydrolyzed by sodium hydroxide, and the resulting carboxyl group is transformed into a acid chloride group, followed by a reaction of this product with isopropylamine gives 1,2-bis-(binzyloxycarbonyl)-1-methyl-2-(p-iso- propylcarbamoyl)benzylhydrazine (30. Hydrolyzis of the benzyloxycarbonyl group in the resulting compound with hydrogen bromide in acetic acid gives the desired procarbazine (30. Along with this, there is an opinion that procarbazine accumulates in cancerous tissue and generates peroxide and hydroperoxide radicals in cells, which imitates the effect of ionizing radiation. It is used for malignant tumors of lymphatic tissue, brain tumors, lung tumors, and Hodgkin’s disease. Asparaginase: Asparaginase is an enzyme that hydrolyzes L-asparagine to L-aspartic acid, which causes a depletion of reserves of L-asparagine, thus inhibiting protein and nucleic acid synthesis. In a medical sense, immunity is a state of having sufficient biological defenses to avoid infection, disease, or other unwanted biological invasion.

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The children’s vanadium came from 1) chronic exposure to car exhaust (a source that constantly invaded their home) discount 200mg red viagra mastercard erectile dysfunction inventory of treatment satisfaction questionnaire, 2) a household gas leak buy cheap red viagra 200 mg erectile dysfunction pump walgreens, or 3) leaking refrigerant (I suspect fossil 19 One might expect that having both toxins would cancel the toxicity. Indeed, the blood proteins are often in normal range for can- cer patients, the problem being masked by this dual toxicity. But in other ways they do not cancel their toxicity, and each takes its toll on your health. Vanadium leaves the body, even from the vital organs, in a week after clean air is supplied and artificial materials are taken out of the mouth. Malonic acid was found to inhibit the use of oxygen by animals (respiration) as early as 1900! By 1930, Otto War- burg had found that anything that inhibited respiration could cause tumor formation. But it was never suspected that tape- worm stages release malonic acid, or that plastic teeth seep it, or that we even eat it in certain common foods. We have seen that some of these common denominators of tumors suppress our oxygen use. And from there, when low immunity allows, they travel to the young tumor and colonize it. This is because bacteria can themselves be infected 21 Geoffrey Zubay, Biochemistry, Addison Wesley Publishing Co. So when the bacteria manage to invade your cell by penetrating the membrane (not an easy job), the virus gets a free ride. Scientists have studied transformation to determine when and how it causes tumor growth but don’t have all the answers. To me, it seems likely that bacteria and their viruses, such as we discuss here, are probably the transforming agents sought by scientists. Of course a dental source will recolonize the digestive tract, so you must stay on this daily dose for protec- tion until the dental source has been removed (see Dental Clean-up, page 73). How Benign Tumors Turn Fatal Tumor growth is a grand conspiracy between parasites, bacteria, fungi, copper, cobalt, vanadium, malonic acid, and assorted carcinogens! But if the tumor enlarges or new ones arise, we know these mechanisms are failing. We should be coming to our body’s assistance rather than shrugging it off as “merely benign. Plus I always observe multiplying Fasciolopsis stages as well as isopropyl alcohol now. Did the Fasciolopsis stages suddenly discover the tumor the way a hermit crab discovers an unused shell? My detection of growth factors in tumors and even the pres- ence of a few fluke stages there suggests we should be much more concerned about them. What has gone wrong in the last cen- tury to permit such a flurry of tumors and cancers? Perhaps this past century has produced the overload of heavy metals, solvents, and globetrotting para- sites required to spark this epidemic. Yet knowing what starts our tumors gives us the power to stop them, whether benign or malignant. Preventing Tumors Will Prevent Cancer Tumors are complex structures, which appear to be asso- ciated with fungi, metals, bacteria, tapeworms, Ascaris and toxins. Being complex, you would think they would be fragile, and removing just one building block would topple them. But the opposite is true: together they form a highly durable oppo- nent for your immune system. Kill tapeworm stages and Ascaris regularly and completely with your parasite killing recipe plus Mop Up. Have only safe dentalware in your mouth since you must suck on this day and night. In fact, it may be the carcinogen that chooses the organ to be targeted for a tumor.

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Alphabetical Listings of Drugs 33 Drug descriptions occasionally mention the following concepts: One drug may be stronger than another cheap red viagra 200mg with visa erectile dysfunction doctors in toms river nj, but such a comparison depends not only on the effect being measured but on the animal species being tested red viagra 200mg sale erectile dysfunction 45 year old male. Frogs, chickens, and rats may react very differently than humans would to an equivalent dose of various drugs. Animal experiments are useful to know about, but the results do not necessarily extrapolate to humans. When this book compares strengths of drugs, the comparison simply gives a rough idea of strengths and has no bearing on determining what size dose of one drug would be equivalent to another size dose of a different substance. When one drug is said to “boost” the effect of another, this means the increase is more than would be expected from simply adding the effect of one drug to the other (1 1 2) but instead involves synergistic chemical and biological processes yielding a total that is more than the combination of parts (1 1 3). Even if all the compounds inside an illicit user can be verified, determining which is responsible for which effect can be challenging. This book’s alphabetical section presents both the conclusions and doubts that scientists express about polydrug use, along with some classic interactions that occur when more than one drug is taken at the same time. Individuals who get into a medical emergency after drug use should bring samples of substances to health care providers; an item may not be what a user thinks it is, and effective treatment must be based on chemical reality rather than consumer belief. The practical meaning of such results is sometimes clouded because the same drug may affect different species in different ways. Also animal tests some- times involve many times the recommended human dose, perhaps levels high enough to poison the animals. These kinds of tests are not meaningless but may involve levels of risk unlikely to be experienced by humans. And yet large doses having no effect on animals do not guarantee a drug’s safety for pregnant women. In some countries a compound called thalidomide was ap- proved for human use after animal tests revealed no potential for causing birth defects, but in humans the substance produced severe congenital malforma- tions such as missing or highly deformed limbs. Experiments testing a drug occasionally produce conflicting results—some may say a drug does something; some may indicate the drug will not do it. These kinds of uncertainties are unsatisfying, but that is the way scientific research operates. Perhaps conflicting results come from differences in dosage 34 The Encyclopedia of Addictive Drugs size, or the manner in which a dose is given, or diet, or living conditions, or any number of other causes. Perhaps the conflict is due to researcher errors—a classic error being failure to run adequate controls (for example, failing to give the drug and a placebo in the same manner to a large number of the same kind of experimental subjects). Conclusions from small stud- ies (that is, studies involving a small number of test subjects) are not as sig- nificant as conclusions from studies measuring thousands of persons. Sometimes drug effect information is based on medical case reports, in which something has happened to one person but has not been experimentally tested to determine how typical the effect is. Another tricky angle occurs when reports say a drug is “associated” with an effect, meaning the drug is administered and an effect follows. In scientific drug reports what scientists say about drugs can be less certain than what public policymakers say. This section of the book strives to present the consensus of mainstream scientific thought. However, sometimes the only available information comes from observations lacking experimental confirmation, at the present time; the reader should keep in mind that by definition such observations are not yet part of a consensus even if they are reported in scientific journals. As dosage increased, so did euphoria and enjoyment of sensual activity such as eating, music, and sex. Various kinds of alcohol exist; many are poisonous, such as wood alcohol, and are not intended for drinking. In former times physicians prescribed alcohol as a treatment for assorted afflictions. That usage is largely outmoded, but alcohol is still a common in- gredient in cough remedies, is applied to skin as a disinfectant, and is a com- ponent of some injectable solutions. Alcohol is used as a partial antidote for methanol poisoning associated with inhalant abuse, and it is used to combat glycol poisoning. In some medical procedures alcohol is administered to create a form of anesthesia called a nerve block. Around 1970 at one hospital a com- bination of alcohol and chloral hydrate was routinely given to make pregnant women unconscious during labor, although alcohol is also a treatment for stopping premature labor. The substance can be a sleep aid (a “nightcap” drink), but researchers have found that it interferes with dreaming, which is an important component of sleep.

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