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Self Control Tests cheap 250mg cefadroxil amex antibiotic used to treat bv, End of Semester Exams buy 250 mg cefadroxil amex antibiotic not working for uti, and Final Exams will be assessed as follows. Self Control Test nd th 2 week: 6 week: Lecture: Proteins, carbohydrates and lipids 3. Fungi: recyclers, pathogens, parasites 2 Differential gene expression in development th 12 week: 1. Lecture: Gene mutation and molecular Differential gene expression in development medicine2. Motion in one dimension, 4 week: displacement, velocity, acceleration, motion Lecture: 7. Discussion of inorganic chemistry Lecture: Nitrogen containing organic com- pounds: the structure and properties of th 4 week: amines. The requirements of these condensed premedical science subjects are very rigorous, thus preparation prior to the beginning the General Medicine, Dentistry or Pharmacy Program is recommended. Students successfully completing the course are directly admitted to their chosen program. Students are encouraged to ask questions related to the topic of the lectures discussed, and participate in solving problems related to the topic of the seminar. Some professors will ask for students to volunteer information, but some professors call on students randomly. It is, thus, a good idea to come to class prepared so as not to be embarrassed in front of the class. The usage of electronic devices, textbooks and any form of interaction between students during the tests is strictly forbidden. Violation of these above mentioned regulations results in an immediate and unconditional dismissal from the program. Attending lectures is strongly recommended, attendance of seminars is compulsory and recorded. Everyone must attend the seminars with the group designated by the Registrar’s Office. Absence can significantly affect your understanding and can have serious implications for progression in your studies. One might have a maximum of six seminar absences to have the opportunity to get exemption. Missed seminars cannot be made up unless one obtains prior permission to be absent. Self Control Tests, End of Semester Exams, and Final Exams will be assessed as follows. Lecture: Nucleic acids and the origin of life Proteins, carbohydrates and lipids 2. Self Control Test th 13 week: th 6 week: Lecture: Fungi: recyclers, pathogens, Lecture: Pathways that harvest chemical parasites 1. Differential gene expression in development Pathways that harvest chemical energy 3. Sensory systems th 20 week: rd Lecture: Salt and Water Balance Nitrogen 23 week: Excretion. Lecture: Animal reproduction and Animal Self Control Test Development The human reproduction system. Rotational motion under Displacement, velocity and acceleration in constant angular acceleration. The camera, the simple magnifier, the Total internal reflection and its medical compound microscope, the telescope and the applications. Atomic, structures for molecular compounds and molecular and molar mass relationships. Substituted carboxylic acids: halo acids, th 13 week: hydroxy acids, keto acids, amino acids. A credit is a relative index of cumulative work invested in a compulsory, a required elective or a freely chosen subject listed in the curriculum. The credit value of a course is based upon the number of lectures, seminars and practical classes of the given subject that should be attended or participated in (so called "contact hours"), and upon the amount of work required for studying and preparing for the examination(s).

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Steroids and immunoglobulin replacement may be used in patients with autoimmune cytopenias or symptomatic hypoglobulinemia (respectively) 250 mg cefadroxil overnight delivery antimicrobial breakpoints. Of the choices given buy cefadroxil 250 mg amex bacteria 5 kingdoms, squamous cell carcinoma is the likeliest expla- nation for this patient’s hemoptysis. Bronchoscopy would likely show the lesion and allow a tissue diagnosis to be made. Adenocarcinoma of the lung is the commonest lung cancer seen in nonsmokers, women, and younger patients. Its incidence is increased in smokers (probably twofold), but not to the degree seen with squamous cell carcinoma and small cell undiffer- entiated carcinoma. Adenocarcinoma is typically peripheral with pleural involvement (rather than the central involvement seen in this case). Bronchoalveolar cell carcinoma arises from alveolar epithelium, is typically peripheral, and may resemble a nonhealing pneumonia (it may even have air bronchograms like a pneumonia). Bronchial adenomas (carcinoid being the commonest type) are often central but are usually smaller and are less common than squamous cell carcinomas. If all three elements (red blood cells, white blood cells, and platelets) are affected, the cause is usually in the bone mar- row (although peripheral destruction from hypersplenism can occasionally cause pancytopenia). In this patient without a history of liver disease or palpable splenomegaly on physical examination, a bone marrow produc- tion problem is the most likely culprit. Although B12 deficiency can cause pancytopenia, usually a macrocytic anemia is the most prominent feature; a serum B12 level would be reasonable, but the most productive approach would be to examine the bone marrow. Leukemia can present without leukocytosis (so-called aleukemic leukemia), but the most likely diagnosis would be aplastic anemia. Pelvic full- ness, vague discomfort, constipation, and early satiety are often the first symptoms of this disease. If the pelvic exam and ultrasound were negative, sigmoidoscopy might be indi- cated to evaluate the patient’s constipation. Pregnancy decreases the risk of ovarian cancer; each pregnancy decreases the risk by about 10%. A family history of ovarian cancer is a major risk factor, increasing a woman’s risk threefold. Coitus early in life and multiple part- ners are risk factors for cervical, but not ovarian, carcinoma. Many patients present with a hematuria or flank pain, but the classic triad of hematuria, flank pain, and a palpable flank mass occurs in only 10 to 20% of patients. Paraneoplastic syndromes such as erythrocytosis, hypercalcemia, hepatic dysfunction, and fever of unknown origin are common. Surgery is the only potentially curable therapy; the results of treatment with chemotherapy or radiation therapy for nonre- sectable disease have been disappointing. Interferon α and interleukin 2 produce responses (but no cures) in 10 to 20% of patients. Radiation therapy is used in metastatic renal carcinoma, but results are disappointing. Immunotherapies such as interferon and interleukin 2 have been used for palliation. Palpation of the scrotal mass and transillumination (holding a flashlight directly against the posterior wall of the scrotum) will distinguish testicular lesions from other masses within the scrotum, such as hydrocele. The lymphatic drainage of the testis is into the periaortic nodes, not to the inguinal nodes. Although benign causes (prostatitis, renal stones) are most common, as many as 30% of patients with gross hematuria will have malignancies of the genitourinary tract. Exposure to ani- line dyes, chronic cyclophosphamide treatment, external beam radiation, and Schistosoma infection of the bladder are other risk factors. This patient should be referred to a urologist for cystoscopy to rule out transitional cell carcinoma of the bladder. Although infectious mononucleosis and toxoplasmosis can cause diffuse lymphadenopathy, these infections are usually associated with other evidence of infection such as pharyngitis, fever, and atypical lymphocytosis in the peripheral blood. It would be unusual for the lymph- adenopathy associated with these infections to persist for 2 months. Serum 186 Medicine angiotensin converting enzyme level is a nonspecific test for sarcoidosis but is also elevated in other granulomatous diseases and is not sensitive or spe- cific enough to be used as an initial diagnostic test.

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This may oc- Hydrostatic pressure is the pressure within the blood cur in bradycardias or tachycardias (inadequate ven- vessel (high in arteries cheap 250 mg cefadroxil amex antibiotics for uti how many days, low in veins) purchase cefadroxil 250mg infection in finger. The loss of consciousness occurs produced by the large molecules within the blood (albu- irrespective of the patient’s posture. A Stokes–Adams min, haemoglobin) and draws water osmotically back attack is a loss of consciousness related to a sudden into the vessel. The hydrostatic pressure is high at the loss of ventricular contraction particularly seen dur- arterial end of a capillary bed hence fluid is forced out of ing the progression from second to third degree heart the vasculature (see Fig. The colloid osmotic pressure then draws fluid back in r Carotid sinus syncope is a rare condition mainly seen at the venous end of the capillary bed as the hydrostatic in the elderly. As a result of hypersensitivity of the carotid sinus, light pressure, such as that exerted by atight collar, causes a severe reflex bradycardia and hence syncope. The syncope results from an inability of the heart to increase cardiac output in response to in- Hydrostatic Oncotic 0ncotic Hydrostatic creased demand. Intermittent claudication Artery Vein Claudication describes a cramp-like pain felt in one or both calves, thighs or buttocks on exertion. This may be a result of blood bypassing fluid is then returned to the circulation via the lymphatic the lungs (right to left shunting) or due to severe lung system. Mechanismsofcardiovascularoedemaincludethefol- lowing: r The arterial pulse Raised venous pressure raising the hydrostatic pres- sure at the venous end of the capillary bed (right ven- The pulse should be palpated at the radial and carotid tricularfailure,pericardialconstriction,venacavalob- artery looking for the following features: struction). The normal pulse is defined as a rate be- which increases the circulating blood volume with tween 60 and 100 beats per minute. Outside this range pooling on the venous side again raising the hydro- it is described as either a bradycardia or a tachycardia. Albumin is the major factor respon- r The character and volume of the pulse are normally sible for the generation of the colloid osmotic pressure assessedatthebrachialorcarotidartery. A drop volume felt at the carotid may be described according in albumin therefore results in an accumulation of to the waveform palpated (see Fig. Radio-femoral delay is suggestive of coarcta- is left after pressing with a thumb for several seconds) tion of the aorta, the lesion being just distal to the or nonpitting. Cardiac oedema is pitting unless long origin of the subclavian artery (at the point where the standing when secondary changes in the lymphatics may ductus arteriosus joined the aorta). Distribution is dependent lay suggests arterial occlusion due to an aneurysm or on the patient. Pleural effusions and Jugular venous pressure ascites may develop in severe failure. The internal jugular vein is most easily seen with the pa- tient reclining (usually at 45˚), with the head supported Cyanosis and the neck muscles relaxed and in good lighting con- Cyanosis is a blue discolouration of the skin and mu- ditions. It is due to the presence of desaturated toid muscle in the upper third of the neck, behind it haemoglobin and becomes visible when levels rise above in the middle third and between the two heads of ster- 5 g/dL. Cyanosis is not present in very anaemic patients nocleidomastoid in the lower third. Cyanosis is divided from the carotid pulse by its double waveform, it is non- into two categories: palpable, it is occluded by pressure and pressure on the r Peripheral cyanosis, which is seen in the fingertips and liver causes a rise in the level of the pulsation (hepato- peripheries. The jugular waveform and pressure give it is due to poor perfusion, as the sluggish circulation information about the pressures within the right atrium leads to increased desaturation of haemoglobin. This as there are no valves separating the atrium and the in- may be as a result of normal vasoconstriction in the ternal jugular vein (see Fig. It is a result of failure of 3cmrepresents an abnormal increase in filling pressure Chapter 2: Clinical 27 Normal The normal pulsation has a rapid rise in pressure followed by a slower phase or reduction in pressure. Slow rising The slow rising pulse is seen in aortic stenosis due to obstruction of outflow. Collapsing The collapsing pulse of aortic regurgitation is characterised by a large upstroke followed by a rapid fall in pressure. This is best appreciated with the arm held up above the head and the pulse felt with the flat of the fingers. Alternans Pulsus alternans describes a pulse with alternating strong and weak beats.

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